4735-54-0

Usage

Structure

A sulfonate ester consisting of a naphthalene group connected to an ethyl chain, which is connected to a 4-methylbenzenesulfonate group.

Usage

Primarily used as a reagent in organic synthesis and as a precursor for the preparation of various pharmaceuticals and agrochemicals.

Medicinal properties

Possesses anti-inflammatory and antihyperalgesic properties, making it a potential candidate for the development of new drugs targeting pain and inflammation.

Toxicity

Known to have low toxicity, making it a valuable building block for the development of new chemical compounds.

Upstream product

• 773-99-9 2-naphthaleneethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 4124-41-8 p-toluenesulfonylanhydride 

Downstream Products

• 417707-59-6 1-[2-(3-methoxy-phenoxy)-ethyl]-naphthalene 
• 417707-60-9 1-{2-[3-(2-methoxy-ethoxy)-phenoxy]-ethyl}-naphthalene 
• 27331-43-7 1-(3-methoxybiphenyl)naphthalene 

Relevant academic research and scientific papers

Bisindolyl maleimide derivative and preparation method and application thereof

The invention provides a bisindolyl maleimide derivative and a preparation method and application thereof. The bisindolyl maleimide derivative has an excellent alpha-glucosidase inhibition effect and can be used for preventing and treating diabetes.

Bisindolylmaleimide derivative, and preparation method and use thereof

The invention provides a bisindolylmaleimide derivative, and a preparation method and a use thereof. The bisindolylmaleimide derivative has a good tumor treatment effect, especially has a good treatment effect on some drug-resistant tumors, and can realize accurate treatment of the drug-resistant tumors.

Melanocortin receptor ligands

Disclosed are MC-4 and/or MC-3 receptor ligands, the ligands having a structure according to Formula (I): wherein R2, R4, R4′, R5, R6, R6′, R7, R8, R8′, R9, R9′, R10, Ar, Z1, Z2, Z3, X, B, D, p, q, r and s are as described in the specification and claims, and optical isomers, diastereomers or enantiomers thereof; pharmaceutically-acceptable salts, hydrates, and biohydrolyzable esters, amides or imides thereof. Also disclosed are pharmaceutical compositions comprising the ligands of Formula (I), as well as methods of treating diseases mediate by the MC-4/MC-3 receptors, as described in the Detailed Descriptions section of the specification.

N1-substituent effects in the selective delivery of polyamine conjugates into cells containing active polyamine transporters

Several N1-arylalkylpolyamines containing various aromatic ring systems were synthesized as their respective HCl salts. The N 1-substituents evaluated ranged in size from N1-benzyl, N1-naphthalen-1-ylmethyl, Ns

Lewis-acid Promoted Aromatic Cyclization of &α-Chlorosulfides: Synthesis of Ethyl Isothiochroman-1-carboxylate and Related Compounds

A variety of ethyl isothiochroman-1-carboxylates and related compounds were synthesized by treatment of 2-chloro-2-acetates with stannic chloride in methylene chloride.The same procedure was applied to the synthesis of ethyl 4-chloro-4-methyltetrahydrothiopyran-2-carboxylate.Some isothiochroman-1-carboxylic acids were prepared and evaluated for antiinflammatory activity.Among the compounds tested, 7-phenoxyisothiochroman-1-carboxylic acid showed weak activity.