473545-53-8Relevant academic research and scientific papers
One-pot preparation of chiral beta-amino esters by rhodium-catalyzed three-components coupling reaction.
Honda, Toshio,Wakabayashi, Hitoshi,Kanai, Kazuo
, p. 307 - 308 (2007/10/03)
Chiral beta-amino esters are synthesized in one-pot from three components, amines, aldehydes, and ethyl bromoacetate, under the rhodium-catalyzed Reformatsky-type reaction condition, where complete diastereoselection is achieved in the nucleophilic addition step of ethyl bromoacetate to the imines prepared in
