473731-78-1

Basic information

• Product Name: Phenol, 2-nitro-6-(1H-tetrazol-5-yl)-
• CAS NO: 473731-78-1
• Molecular Formula: C7H5N5O3
• Molecular Weight: 207.148
• Mol File: 473731-78-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 2-nitro-6-(1H-tetrazol-5-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-nitro-6-(1H-tetrazol-5-yl)-(473731-78-1)
• EPA Substance Registry System: Phenol, 2-nitro-6-(1H-tetrazol-5-yl)-(473731-78-1)

Safety Data

• Hazardous Substances Data: 473731-78-1(Hazardous Substances Data)

Upstream product

• 51449-77-5 2-(1H-tetrazol-5-yl)phenol 

Relevant articles and documents

THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of Formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and ischemia reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of Formula (IA).

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.