473775-39-2Relevant academic research and scientific papers
Synthesis of (1S,2R)-1-phenyl-2-[(S)-1-aminoalkyl]-N,N-diethylcyclopropanecarboxamides as novel NMDA receptor antagonists having a unique NMDA receptor subtype selectivity
Kazuta, Yuji,Tsujita, Ryuichi,Uchino, Shigeo,Kamiyama, Noriko,Mochizuki, Daisuke,Yamashita, Kanako,Ohmori, Yutaka,Yamashita, Akitake,Yamamoto, Tamotsu,Kohsaka, Shinich,Matsuda, Akira,Shuto, Satoshi
, p. 1199 - 1212 (2002)
(1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (2b), which is a conformationally restricted analog of the antidepressant milnacipran [(±)-1], is a new class of potent NMDA (N-methyl-D-aspartic acid) receptor antagonists. A serie
