473910-23-5

Upstream product

• 54276-69-6 2-nitrobenzyl (4-nitrophenyl) carbonate 
• 961-07-9 2'-Deoxyguanosine 
• 612-25-9 2-Nitrobenzyl alcohol 

Downstream Products

• 473910-28-0 C₄₆H₄₁N₇O₁₂ 
• 473910-26-8 C₃₇H₄₉N₇O₁₁Si₂ 
• 473910-27-9 C₂₅H₂₃N₇O₁₀ 
• 473910-25-7 [6-Oxo-9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-6,9-dihydro-1H-purin-2-yl]-carbamic acid 2-nitro-benzyl ester 
• 961-07-9 2'-Deoxyguanosine 

Relevant academic research and scientific papers

Photolabile groups for exocyclic amino and O6/N-1 lactam protection in oligonucleotide synthesis

The use of o-nitrobenzyloxycarbonyl (nCbz) for direct protection of exocyclic amino function of nucleosides viz. adenosine, cytidine and deoxyguanosine using o-nitrobenzyl-p-nitrophenyl carbonate as a reagent and O6-derivatization of deoxyguanosine with o-nitrobenzyl (nBzl) using o-nitrobenzyldiazomethane as a reagent is being reported. Both these protected groups could be cleaved by irradiation at 354nm to yield valuable building blocks for oligonucleotide synthesis.