473916-33-5Relevant academic research and scientific papers
1,2-DISUBSTITUTED-4-BENZYLAMINO-PYRROLIDINE DERIVATIVES AS CETP INHIBITORS USEFUL FOR THE TREATMENT OF DISEASES SUCH AS HYPERLI PIDEMIA OR ARTERIOSCLEROSIS
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Page/Page column 77, (2009/07/17)
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
Efficient synthesis of the κ-opioid receptor agonist CJ-15,161: Four stereospecific inversions at a single aziridinium stereogenic center
Couturier, Michel,Tucker, John L.,Andresen, Brian M.,DeVries, Keith M.,Vanderplas, Brian C.,Ito, Fumitaka
, p. 3517 - 3523 (2007/10/03)
An efficient four-step sequence has been developed for the synthesis of the κ-opioid receptor agonist CJ-15,161. The process features four consecutive regioselective and stereospecific inversions at a single aziridinium stereogenic center, which leads to
Process for preparing hydroxypyrrolidinyl ethylamine compounds useful as kappa agonists
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, (2008/06/13)
A process of preparing compounds having the formula I: or an optical isomer or racemic or optically active mixture thereof, which are useful as selective kappa-receptor agonists.
