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1',2'-Dihydrospiro[cyclohexane-1,3'-indole] is a chemical compound characterized by a spiro[4.5]decan-6-one backbone fused with an indole ring. This spiro compound exhibits potential biological activity and serves as a valuable precursor in the synthesis of diverse indole derivatives. It has demonstrated promising pharmacological properties, such as antihypertensive, antidepressant, and neuroprotective effects, making it a significant entity in medicinal chemistry research for the development of innovative drugs and pharmaceuticals. Furthermore, 1',2'-dihydrospiro[cyclohexane-1,3'-indole] has garnered interest in studies exploring its chemical and physical characteristics, along with its potential applications across various industrial and academic sectors.

4740-63-0

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4740-63-0 Usage

Uses

Used in Pharmaceutical Industry:
1',2'-Dihydrospiro[cyclohexane-1,3'-indole] is utilized as a precursor in the synthesis of indole derivatives for the development of new drugs and pharmaceuticals. Its potential pharmacological activities, including antihypertensive, antidepressant, and neuroprotective properties, make it a promising candidate for the treatment of various medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1',2'-dihydrospiro[cyclohexane-1,3'-indole] is employed as a key compound for studying its chemical and physical properties. This research aids in understanding its potential applications and contributes to the advancement of drug discovery and development processes.
Used in Chemical and Physical Property Studies:
1',2'-Dihydrospiro[cyclohexane-1,3'-indole] is also used in academic and industrial settings for investigating its chemical and physical properties. These studies provide insights into the compound's behavior and interactions, which can be instrumental in identifying new applications and optimizing its use in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 4740-63-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,4 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4740-63:
(6*4)+(5*7)+(4*4)+(3*0)+(2*6)+(1*3)=90
90 % 10 = 0
So 4740-63-0 is a valid CAS Registry Number.

4740-63-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name spiro[1,2-dihydroindole-3,1'-cyclohexane]

1.2 Other means of identification

Product number -
Other names 1',2'-dihydro-spiro[cyclohexane-1,3'-[3H]indole]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4740-63-0 SDS

4740-63-0Relevant academic research and scientific papers

SYNTHESIS OF 1'-(3-DIMETHYLAMINOPROPYL)-2'-SUBSTITUTED SPIRO.

Rodriguez, Jose-Gonzalo,Temprano, Fernando

, p. 3243 - 3248 (2007/10/02)

Reactivity of the C=N bond in spiro has been analysed.Indolines were obtained in practically quantitative yield using organomagnesium reagents in the presence of copper(I) chloride in toluene at 120 deg C.On the basis of an an

REACTION OF SPIRO WITH GRIGNARD REAGENTS IN THE PRESENCE OF CUPROUS CHLORIDE

Rodriguez, Gonzalo,Benito, Yolanda,Temprano, Fernando

, p. 427 - 428 (2007/10/02)

Attack of MeMgI and PhMgBr in toluene on spiro (1) in the presence of Cu2Cl2 gives 2'-substituted spiro in quantitative yields.Also, attack of PhCH2CH2MgBr on 1 in the presence of Cu2Cl2 afforded 2'-phenethyl, 2'-H and 2'-benzyl (or 2'-p-xylyl) derivatives in toluene (or p-xylene) as solvent.

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