474095-35-7

Upstream product

• 474095-34-6 3-(amino-(benzamido)-methylene)-4,5-dihydro-4-phenyl-2(3H)-furanone 
• 474095-32-4 3-diaminomethylene-4,5-dihydro-4-phenyl-2(3H)-furanone 
• 59790-95-3 2-amino-4,5-dihydro-4-phenyl-3-furancarbonitrile 
• 34884-15-6 2-amino-4,5-dihydro-4-phenyl-3-furancarboxamide 

Downstream Products

• 34971-29-4 methyl tetrahydro-2-oxo-4-phenyl-3-furancarboxylate 

Relevant academic research and scientific papers

Synthesis of 3-diaminomethylene-2(3H)-furanones by reaction of 2-amino-4,5-dihydro-3-furancarboxamides with amines

The reaction of 2-amino-4,5-dihydro-3-furancarboxamides with morpholine in the presence of acetic acid in pyridine or under the influence of ammonium acetate gave the corresponding 3-diaminomethylene-4,5-dihydro-2(3H)-furanones; 4,5-dihydro-2-morpholino-3-furancarboxamides were not isolated. One of the former reacted with benzylamine to give (E)- and (Z)-3-(amino-(benzylamino)-methylene)-4,5-dihydro-4-phenyl-2(3H)-furanones and 2-benzylamino-4,5-dihydro-4-phenyl-3-furancarboxamide.