4742-77-2

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 15781-70-1 malonic acid bis-(2,4,6-trichloro-phenyl) ester 

Downstream Products

• 1262872-46-7 4-bromo-N'-{[8-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-3(4H)-ylidene]methyl}benzohydrazide 
• 1262872-39-8 3-[(4-fluoroanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-36-5 3-[(mesitylamino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-40-1 8-methyl-3-[(2-sulfanylanilino)methylidene]-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-45-6 4-nitro-N'-{[8-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-3(4H)-ylidene]methyl}benzohydrazide 
• 1262872-47-8 4-chloro-N'-{[8-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-3(4H)-ylidene]methyl}benzohydrazide 
• 1262872-48-9 4-hydroxy-N'-{[8-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-3(4H)-ylidene]methyl}benzohydrazide 
• 1262872-44-5 N'-{[8-methyl-2,4-dioxo-2H-pyrido[1,2-a]pyrimidin-3(4H)-ylidene]methyl}benzohydrazide 
• 1262872-35-4 3-[(4-acetylanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-33-2 3-[(2-acetylanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-34-3 3-[(3-acetylanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-37-6 3-[(2-fluoroanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 
• 1262872-38-7 3-[(3-fluoroanilino)methylidene]-8-methyl-2H-pyrido[1,2-a]pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Electro-organic reactions part 35. Efficient carbon-oxygen bond formation in the anodic coupling of pyridopyrimidine derivatives

4-H-Pyrido[1,2-a]pyrimidine-2,4-diones (Chichibabin) derivatives, formed by condensation of 2-aminopyridines with substituted dialkylmalonates, are electroactive. In solution in CH2Cl2/CF3CO2H mixtures they are smoothly and selectively anodically coupled in high yield. The products are novel and unexpected; radical coupling at the C-3 and O-4 positions is involved and the proposed mechanism is analogous to that of oxidative phenolic coupling.