474448-79-8Relevant academic research and scientific papers
Pharmacophore-based search, synthesis, and biological evaluation of anthranilic amides as novel blockers of the Kv1.5 channel
Peukert, Stefan,Brendel, Joachim,Pirard, Bernard,Struebing, Carsten,Kleemann, Heinz-Werner,Boehme, Thomas,Hemmerle, Horst
, p. 2823 - 2827 (2004)
The search for novel, potent Kv1.5 blockers based on an anthranilic amide scaffold employing a pharmacophore-based virtual screening approach is described. The synthesis and structure-activity relationships (SAR) with respect to inhibition of the Kv1.5 ch
