4745-93-1

Basic information

• Product Name: 4,7-Diazaindole
• Synonyms: 4,7-DIAZAINDOLE,5H-PYRROLO[2,3-B]PYRAZINE;5H-Pyrrolo[2,3-b]pyrazine;4,7-Diazaindole
• CAS NO: 4745-93-1
• Molecular Formula: C₆H₅N₃
• Molecular Weight: 119.12
• Product Categories: Heterocycles series;Azaindoles
• Mol File: 4745-93-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 155-156 °C
• Boiling Point: 236 °C
• Flash Point: 96 °C
• Appearance: /
• Density: 1.38
• Refractive Index: 1.715
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.95±0.20(Predicted)
• CAS DataBase Reference: 4,7-Diazaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-Diazaindole(4745-93-1)
• EPA Substance Registry System: 4,7-Diazaindole(4745-93-1)

Safety Data

• Hazardous Substances Data: 4745-93-1(Hazardous Substances Data)

Usage

Uses

5H-pyrrolo[2,3-b]pyrazine was studied and discovered to be a novel ERK2 inhibitors.

InChI:InChI=1/C6H5N3/c1-2-8-6-5(1)7-3-4-9-6/h1-4H,(H,8,9)

Upstream product

• 1165803-10-0 C₇H₇N₃O₂S 
• 1066-54-2 trimethylsilylacetylene 
• 724442-38-0 N-(3-chloropyrazin-2-yl)-methanesulfonamide 

Downstream Products

• 4121-22-6 5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 
• 1316228-34-8 tert-butyl 7-(1-benzyltriazol-4-yl)pyrrolo[2,3-b]pyrazine-5-carboxylate 
• 889451-26-7 7-iodo-5H-pyrrolo[2,3-b]pyrazine 
• 1316228-57-5 7-(1-benzyl-1H-1,2,3-triazol-4-yl)-5H-pyrrolo-[2,3-b]pyrazine 
• 300545-99-7 C₂₇H₂₅N₃O₅ 

Relevant articles and documents

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PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS

Compounds of the general formula(I): (I) processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

6-Substituted-5H-pyrrolo[2,3-b]pyrazines via palladium-catalyzed heteroannulation from N-(3-chloropyrazin-2-yl)-methanesulfonamide and alkynes

We herein report the efficient and convenient synthesis of 6-substituted-5H-pyrrolo[2,3-b]pyrazines. The reaction is a palladium-catalyzed heteroannulation process followed by deprotection to yield the desired pyrrolo[2,3-b]pyrazine substrates. The reacti