47465-97-4

Basic information

• Product Name: 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on
• Synonyms: 1,3-DIHYDRO-3,3-BIS(4-HYDROXY-3-METHYLPHENYL)-2H-INDOL-2-ONE;1,3-dihydro-3,3-bis(4-hydroxy-m-tolyl)-2H-indol-2-one;1,3-DIHYDRO-3,3-BIS(4-HYDROXY-3-METHYLPHENYL)-2H-INDOL-2-ONE (IBK=ISATIN-BIS-CRESOL );1,3-Dihydro-3,3-bis(4-hydroxy-3-methylphenyl)-2H-indol-2-oneSynonym:Isatin-bis-cresol(IBK);Isatin-bis-cresol=IBK;2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxy-3-methylphenyl)-;Isatin-bis-cresol;1,3-DIHYDRO-3,3-BIS(4-HYDROXY-3-METHYLPHENYL)-2H-I
• CAS NO: 47465-97-4
• Molecular Formula: C₂₂H₁₉NO₃
• Molecular Weight: 345.39
• EINECS: 256-318-7
• Product Categories: Organics;Amines;Aromatics;Heterocycles
• Mol File: 47465-97-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 560.4°Cat760mmHg
• Flash Point: 292.7°C
• Appearance: /
• Density: 1.292g/cm³
• Vapor Pressure: 3.66E-13mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 9.81±0.35(Predicted)
• CAS DataBase Reference: 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on(47465-97-4)
• EPA Substance Registry System: 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on(47465-97-4)

Safety Data

• Statements: 20/21/22
• Safety Statements: 36/37
• RIDADR: 2811
• Hazardous Substances Data: 47465-97-4(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

Different sources of media describe the Uses of 47465-97-4 differently. You can refer to the following data:
1. It is useful as a material for polycarbonates.
2. 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on is useful as a material for polycarbonates

InChI:InChI=1/C22H19NO3/c1-13-11-15(7-9-19(13)24)22(16-8-10-20(25)14(2)12-16)17-5-3-4-6-18(17)23-21(22)26/h3-12,24-25H,1-2H3,(H,23,26)

Upstream product

• 91-56-5 indole-2,3-dione 
• 95-48-7 ortho-cresol 
• 39033-45-9 3,3-dichloro-2,3-dihydro-1H-indol-2-one 

Relevant articles and documents

Lambert Salt-Initiated Development of Friedel–Crafts Reaction on Isatin to Access Distinct Derivatives of Oxindoles

Herein, a mild metal-free and efficacious route for the synthesis of biologically important 3-aryl oxindole derivatives is described. Using Lambert salt-initiated hydroarylation of isatin, a diverse array of monoarylated products, symmetrical/unsymmetrical double-arylated products, and deoxygenated hydroarylated products could be synthesized from the single starting substrate in good to excellent yields. A preliminary mechanistic study revealed that the reaction proceeds via a monoarylated product followed by a nucleophilic attack by another electron-rich arene nucleophile under mild conditions. The potential of newly synthesized symmetric/unsymmetric 3,3-disubstituted oxindole, 3-substituted 3-hydroxy oxindoles, 3,3-di(indolyl)indolin-2-ones, and α-aryl oxindoles as valuable building blocks is further illustrated.