4747-68-6

Usage

Uses

Used in the Production of Polyurethane Foam:
CYCLOHEPTYL ISOCYANATE is used as a key chemical intermediate for the production of polyurethane foam, a versatile material known for its lightweight, flexible, and durable properties. It is utilized in various applications, including furniture, bedding, automotive seating, and insulation.
Used in the Manufacturing of Adhesives:
In the adhesives industry, CYCLOHEPTYL ISOCYANATE serves as a critical component in the formulation of high-performance adhesives. These adhesives are valued for their strong bonding capabilities, resistance to various environmental conditions, and versatility in adhering to different substrates.
Used in the Creation of Coatings:
CYCLOHEPTYL ISOCYANATE is employed as a vital ingredient in the development of coatings, which are applied to protect and enhance the appearance of various surfaces. These coatings are appreciated for their durability, resistance to wear and tear, and ability to provide a smooth, aesthetically pleasing finish.

InChI:InChI=1/C8H13NO/c10-7-9-8-5-3-1-2-4-6-8/h8H,1-6H2

Upstream product

• 1118-02-1 trimethylsilyl isocyanate 
• 291-64-5 cycloheptane 
• 1459-39-8 cycloheptanecarboxamide 
• 75-44-5 phosgene 
• 5452-35-7 cycloheptanamine 

Downstream Products

• 52068-98-1 C₂₄H₃₂N₄O₄S 
• 52068-91-4 C₂₅H₃₄N₄O₄S 
• 20921-64-6 N-Cycloheptyl-carbaminsaeure-<3-(4-fluor-phenyl)-3-phenyl-propin-(1)-yl-(3)>-ester 
• 20921-62-4 N-Cycloheptyl-carbaminsaeure-<3-(p-chlor-phenyl)-3-phenyl-propin-(1)-yl-(3)>-ester 
• 469-22-7 eseroline 
• 1287760-99-9 4-{3-[3-(3-cycloheptyl-ureido)-propyl]-5-phenyl-pyrazol-1-yl}-benzenesulfonamide 
• 1072113-11-1 5-(4-chlorophenyl)-N-(cycloheptylcarbamoyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide 
• 1028991-61-8 C₂₆H₃₁ClF₃N₃O 
• 1028991-57-2 C₂₆H₃₄ClN₃O 
• 1028991-53-8 C₂₅H₃₁Cl₂N₃O 

Relevant academic research and scientific papers

Alkyl Isocyanates via Manganese-Catalyzed C-H Activation for the Preparation of Substituted Ureas

Organic isocyanates are versatile intermediates that provide access to a wide range of functionalities. In this work, we have developed the first synthetic method for preparing aliphatic isocyanates via direct C-H activation. This method proceeds efficiently at room temperature and can be applied to functionalize secondary, tertiary, and benzylic C-H bonds with good yields and functional group compatibility. Moreover, the isocyanate products can be readily converted to substituted ureas without isolation, demonstrating the synthetic potential of the method. To study the reaction mechanism, we have synthesized and characterized a rare MnIV-NCO intermediate and demonstrated its ability to transfer the isocyanate moiety to alkyl radicals. Using EPR spectroscopy, we have directly observed a MnIV intermediate under catalytic conditions. Isocyanation of celestolide with a chiral manganese salen catalyst followed by trapping with aniline afforded the urea product in 51% enantiomeric excess. This represents the only example of an asymmetric synthesis of an organic urea via C-H activation. When combined with our DFT calculations, these results clearly demonstrate that the C-NCO bond was formed through capture of a substrate radical by a MnIV-NCO intermediate.

Novel guanidinobenzamides

Compounds of formula IA and IB are new where the variables R1 through R10 have the values set forth herein. Such compounds have use in treating diseases such as obesity and type II diabetes, and may be provided as pharmaceutical form

SYNTHESIS OF ALIPHATIC ISOCYANATES VIA A TWO-PHASE HOFMANN REACTION

A convenient method of preparing aliphatic isocyanates via a two-phase Hofmann reaction using a phase transfer catalyst is described.