474826-38-5Relevant academic research and scientific papers
Lewis base catalyzed aldol additions of chiral trichlorosilyl enolates and silyl enol ethers
Denmark, Scott E.,Fujimori, Shinji,Pham, Son M.
, p. 10823 - 10840 (2005)
The consequences of double diastereodifferentiation in chiral Lewis base catalyzed aldol additions using chiral enoxysilanes derived from lactate, 3-hydroxyisobutyrate, and 3-hydroxybutyrate have been investigated. Trichlorosilyl enolates derived from the
The effects of a remote stereogenic center in the Lewis base catalyzed aldol additions of chiral trichlorosilyl enolates
Denmark, Scott E.,Fujimori, Shinji
, p. 3477 - 3480 (2007/10/03)
(matrix presented) Chiral trichlorosilyl enolates bearing a remote stereogenic center were employed in the phosphoramide-catalyzed aldol reaction. The additions of the methyl ketone enolates proceeded with only moderate diastereoselectivities. The additio
