474917-91-4

Upstream product

• 623563-64-4 2-(4-aminobutoxy)-6-benzyloxybenzoic acid methyl ester 
• 474917-90-3 methyl 2-[4-({N-(tert-butoxycarbonyl)-4-[(3-ethoxy-1-ethyl-3-oxopropyl)amino]-L-phenylalanyl}amino)butoxy]-6-hydroxybenzoate 
• 4755-77-5 Ethyl oxalyl chloride 
• 623563-65-5 2-{4-[3-(4-amino-phenyl)-2-tert-butoxycarbonylamino-propionylamino]-butoxy}-6-benzyloxy-benzoic acid methyl ester 
• 55533-24-9 L-N-tert-butoxycarbonyl-p-aminophenylalanine 

Relevant academic research and scientific papers

Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors

A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous mem

Selective protein tyrosine phosphatatase inhibitors

Compounds of formula (I) or therapeutically acceptable salts thereof, are selective protein tyrosine kinase-B (PTP1B) inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of disorders using the compounds are disclosed.