623563-65-5Relevant academic research and scientific papers
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors
Pei, Zhonghua,Li, Xiaofeng,Liu, Gang,Abad-Zapatero, Cele,Lubben, Tom,Zhang, Tianyuan,Ballaron, Stephen J.,Hutchins, Charles W.,Trevillyan, James M.,Jirousek, Michael R.
, p. 3129 - 3132 (2003)
A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous mem
