475040-19-8

Basic information

• Product Name: N-(2-bromo-2-cyclohexenyl)-2-fluoro-N-methylaniline
• Synonyms: N-(2-bromo-2-cyclohexenyl)-2-fluoro-N-methylaniline
• CAS NO: 475040-19-8
• Molecular Weight: 284.171
• Mol File: 475040-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-2-cyclohexenyl)-2-fluoro-N-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-2-cyclohexenyl)-2-fluoro-N-methylaniline(475040-19-8)
• EPA Substance Registry System: N-(2-bromo-2-cyclohexenyl)-2-fluoro-N-methylaniline(475040-19-8)

Safety Data

• Hazardous Substances Data: 475040-19-8(Hazardous Substances Data)

Upstream product

• 17202-32-3 1,6-dibromocyclohex-1-ene 
• 1978-38-7 2-fluoro-N-methylaniline 
• 348-54-9 2-Fluoroaniline 

Relevant articles and documents

Synthesis of functionalized indole- and benzo-fused heterocyclic derivatives through anionic benzyne cyclization

The development of a new method for the regioselective synthesis of functionalized indoles and six-membered benzo-fused N-, O-, and S-heterocycles is reported. The key step involves the generation of a benzyne-tethered vinyl or aryllithium compound that undergoes a subsequent intramolecular anionic cyclization. Reaction of the organolithium intermediates with selected electrophiles allows the preparation of a wide variety of indole, tetrahydrocarbazole, dihydrofenantridine, dibenzopyran, and dibenzothiopyran derivatives. Finally, the application of this strategy to the appropriate starting materials allows the preparation of some tryptamine and serotonin analogues.