475051-48-0

Upstream product

• 475051-59-3 (Z)-(4S,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-4,6-dimethyl-hept-2-enoic acid methyl ester 
• 475051-58-2 (2S,3S,4S)-3-(tert-butyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-2,4-dimethylpentanol 
• 475051-47-9 (2R,3R,4S)-3-(tert-butyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-2,4-dimethylpentanal 
• 475051-57-1 (2R,3S,4S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid ethyl ester 
• 443761-71-5 (2R,3S,4S)-3,5-bis(tert-butyldimethylsilyloxy)-2,4-dimethylpentan-1-ol 
• 475051-45-7 (2R,3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanoic acid ethyl ester 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 475051-60-6 (Z)-(4S,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-4,6-dimethyl-hept-2-en-1-ol 

Downstream Products

• 625109-71-9 phenyl (3R,4Z,6S,7S,8S)-7-(tert-butyldimethylsiloxy)-9-(tert-butyldilphenylsiloxy)-3-hydroxy-6,8-dimethyl-4-nonenoate 
• 475051-49-1 phenyl (3S,4Z,6S,7S,8S)-7-(tert-butyldimethylsiloxy)-9-(tert-butyldilphenylsiloxy)-3-hydroxy-6,8-dimethyl-4-nonenoate 

Relevant academic research and scientific papers

A straightforward, highly stereoselective construction of eight stereogenic centers in (+)-discodermolide C1-C13 segment, based on a strategy of iterative aldol reactions

The eight stereogenic centers were introduced into the C1-C13 segment of (+)-discodermolide by iterative aldol reactions with quite a high level of selection.