475051-58-2

Upstream product

• 475051-45-7 (2R,3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanoic acid ethyl ester 
• 625109-58-2 ethyl (2S,3R,4S)-2-bromo-5-(tert-butyldiphenylsiloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 625109-63-9 ethyl (2R,3R,4S)-5-(tert-butyldiphenylsiloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 475051-57-1 (2R,3S,4S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid ethyl ester 
• 443761-71-5 (2R,3S,4S)-3,5-bis(tert-butyldimethylsilyloxy)-2,4-dimethylpentan-1-ol 
• 374896-36-3 ethyl (2R,3S,4S)-2-bromo-5-(tert-butyldimethylsiloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 123284-89-9 (+/-)-2-methyl-3-[(tert-butyldiphenylsilyl)oxy]propanal 
• 129029-85-2 (2RS)-3-(tert-butyldiphenylsilyloxy)-2-methylpropanol 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 625109-64-0 ethyl (2R,3R,4S)-3-(tert-butyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-2,4-dimethylpentanoate 
• 475051-46-8 (2S,3S,4S)-1-(tert-butyldiphenylsiloxy)-3,5-di-(tert-butyldimethylsiloxy)-2,4-dimethylpentane 
• 625109-61-7 ethyl (2S,3R,4S)-5-(tert-butyldiphenylsiloxy)-2-bromo-3-methoxymethoxy-2,4-dimethylpentanoate 

Downstream Products

• 475051-60-6 (Z)-(4S,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-4,6-dimethyl-hept-2-en-1-ol 
• 475051-59-3 (Z)-(4S,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-4,6-dimethyl-hept-2-enoic acid methyl ester 
• 475051-48-0 (Z)-(4S,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-4,6-dimethyl-hept-2-enal 
• 475051-47-9 (2R,3R,4S)-3-(tert-butyldimethylsiloxy)-5-(tert-butyldiphenylsiloxy)-2,4-dimethylpentanal 

Relevant academic research and scientific papers

Stereopentads derived from a sequence of Mukaiyama aldolization and free radical reduction on α-methyl-β-alkoxy aldehydes: A general strategy for efficient polypropionate synthesis

(Chemical Equation Presented) In a stereodivergent manner, all 16 diastereomeric stereopentads 7-22 were synthesized starting with α-methyl-β-alkoxy aldehydes 25 and 27. We designed an approach based on a sequence of a Mukaiyama aldolization with enoxysil

Regulated-stereoselective construction of thirteen stereogenic centers necessary for the frame of (+)-discodermolide, based on iterative Lewis acid-promoted aldol reactions

The segments C1-C13 and C15-C 21 containing the 13 stereogenic centers required for the frame of (+)-discodermolide were synthesized in good to excellent enantio- and diastereoselectivities from a common racemic

A straightforward, highly stereoselective construction of eight stereogenic centers in (+)-discodermolide C1-C13 segment, based on a strategy of iterative aldol reactions

The eight stereogenic centers were introduced into the C1-C13 segment of (+)-discodermolide by iterative aldol reactions with quite a high level of selection.