475060-18-5 Usage
General Description
2-Acetamido-5-amino-4-picoline is a chemical compound with the molecular formula C8H10N4O. It is a derivative of picoline, which is a heterocyclic aromatic compound similar to pyridine. 2-ACETAMIDO-5-AMINO-4-PICOLINE contains an acetamido group and an amino group on the picoline ring. It is often used as a building block or intermediate in the synthesis of pharmaceuticals and other organic compounds. 2-Acetamido-5-amino-4-picoline may also have potential biological activities and may be studied for its potential pharmacological properties. This chemical is of interest to researchers and scientists in the fields of medicinal chemistry, organic synthesis, and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 475060-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,0,6 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 475060-18:
(8*4)+(7*7)+(6*5)+(5*0)+(4*6)+(3*0)+(2*1)+(1*8)=145
145 % 10 = 5
So 475060-18-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3O/c1-5-3-8(11-6(2)12)10-4-7(5)9/h3-4H,9H2,1-2H3,(H,10,11,12)
475060-18-5Relevant articles and documents
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety
Nakayama, Kiyoshi,Kuru, Noriko,Ohtsuka, Masami,Yokomizo, Yoshihiro,Sakamoto, Atsunobu,Kawato, Haruko,Yoshida, Ken-Ichi,Ohta, Toshiharu,Hoshino, Kazuki,Akimoto, Katsuya,Itoh, Junko,Ishida, Hiroko,Cho, Aesop,Palme, Monica H.,Zhang, Jason Z.,Lee, Ving J.,Watkins, William J.
, p. 2493 - 2497 (2007/10/03)
Exchange of the ethylene tether in a series of pyridopyrimidine-based MexAB-OprM specific efflux pump inhibitors to an amide bond stabilized the olefin of the acrylic acid moiety, preventing facile photoisomerization to the Z-isomer. Furthermore, the activity was drastically improved in the amide tether variants, providing extremely potent acrylic acid and vinyl tetrazole analogues.
