90765-02-9

Basic information

• Product Name: 2-ACETAMIDO-5-NITRO-4-PICOLINE
• Synonyms: 2-ACETAMIDO-5-NITRO-4-PICOLINE;2-Acetamido-5-nitro-picoline;4-Picoline,2-acetamido-5-nitro- (7CI);N-(4-Methyl-5-nitro-2-pyridinyl)-acetamide;N-(4-Methyl-5-nitropyridin-2-yl)acetamide
• CAS NO: 90765-02-9
• Molecular Formula: C₈H₉N₃O₃
• Molecular Weight: 195.18
• Product Categories: Pyridine;Heterocyclic Compounds;Pyridines
• Mol File: 90765-02-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 157℃
• Boiling Point: 421.508 °C at 760 mmHg
• Flash Point: 208.721 °C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 2-ACETAMIDO-5-NITRO-4-PICOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETAMIDO-5-NITRO-4-PICOLINE(90765-02-9)
• EPA Substance Registry System: 2-ACETAMIDO-5-NITRO-4-PICOLINE(90765-02-9)

Safety Data

• Hazardous Substances Data: 90765-02-9(Hazardous Substances Data)

Usage

General Description

2-Acetamido-5-nitro-4-picoline is a chemical compound that belongs to the class of picoline derivatives. It is a yellow crystalline solid with a molecular formula of C7H7N3O3. 2-ACETAMIDO-5-NITRO-4-PICOLINE is used in the manufacturing of pharmaceuticals and agrochemicals, and it also has potential applications in the field of organic synthesis. Its properties and reactivity make it useful for various chemical reactions and processes. Additionally, 2-acetamido-5-nitro-4-picoline is also being studied for its potential biological activities and could have potential medical applications in the future.

InChI:InChI=1/C8H9N3O3/c1-5-3-8(10-6(2)12)9-4-7(5)11(13)14/h3-4H,1-2H3,(H,9,10,12)

Upstream product

• 21901-40-6 2-amino-5-nitro-4-picoline 
• 108-24-7 acetic anhydride 

Downstream Products

• 174610-12-9 1H-pyrrolo[2,3-c]pyridin-5-amine 
• 174610-11-8 N-(1H-pyrrolo[2,3-c]pyridin-5-yl)acetamide 
• 475060-22-1 tert-butyl N-(5-fluoro-4-methyl-pyridin-2-yl)carbamate 
• 475060-21-0 N₁-(5-fluoro-4-methyl-pyridin-2-yl)acetamide 
• 301222-66-2 2-amino-5-fluoro-4-methylpyridine 
• 475060-18-5 N₁-(5-amino-4-methyl-pyridin-2-yl)acetamide 

Relevant articles and documents

Indole-2-ketone derivative, preparation method and application thereof

The invention belongs to the field of medicines, particularly relates to an indole-2-ketone derivative, a preparation method and application thereof, and provides a compound represented by the following formula (I), a stereoisomer, a racemate, a tautomer,

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

Drug efflux pump inhibitor

A medicament for preventive and/or therapeutic treatment of a microbial infection which comprises as an active ingredient a compound represented by the following general formula (I): wherein, R1 and R2 represent hydrogen atom, a halogen atom, hydroxyl group or the like, W1 represents —CH═CH—, —CH2O—, —CH2CH2— or the like; R3 represents hydrogen atom, a halogen atom, hydroxyl group or an amino group; R4 represents hydrogen atom, a group of —OZ0-4R5 (Z0-4 represents an alkylene group, a fluorine-substituted alkylene group or a single bond, and R5 represents a cyclic alkyl group, an aryl group or the like); W2 represents a single bond or —C(R8)═C(R9)— (R8 and R9 represent hydrogen atom, a halogen atom, a lower alkyl group or the like, Q represents an acidic group, but W2 and Q may together form vinylidenethiazolidinedione or an equivalent heterocyclic ring; m and n represent an integer of 0 to 2, and q represents an integer of 0 to 3.