475086-22-7Relevant academic research and scientific papers
Diphenylpyrazine compound or pharmaceutically acceptable salt and isomer as well as preparation method and application thereof
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Paragraph 0099-0101, (2018/12/14)
The invention provides a diphenylpyrazine compound or a pharmaceutically acceptable salt and an isomer with a structure expressed as a formula which is as shown in description. The diphenylpyrazine compound or the pharmaceutically acceptable salt and the
HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES
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Page 56, (2010/02/05)
The present invention provides a compound which is useful as a PGI2 receptor agonist, and a pharmaceutical composition. The present invention is directed to a pharmaceutical composition comprising a compound represented by the following formula [1]: (R1 and R2 are the same or different and each represents optionally substituted aryl, Y represents N or CH, Z represents N or CH, A represents NH, NR5, O, S, or ethylene, R5 represents alkyl, D represents alkylene or alkenylene, E represents phenylene or single bond, G represents O, S, or CH2, R3 and R4 are the same or different and each represents hydrogen or alkyl, Q represents carboxy, alkoxycarbonyl, tetrazolyl, carbamoyl, or N-(alkylsulfonyl)carbamoyl), or a pharmaceutically acceptable salt thereof as an active ingredient.
