475094-43-0

Basic information

• Product Name: 5-METHYLTHIO-1,3,4-TRIPHENYL-1H-PYRAZOLE
• Synonyms: 5-METHYLTHIO-1,3,4-TRIPHENYL-1H-PYRAZOLE
• CAS NO: 475094-43-0
• Molecular Formula: C22H18N2S
• Molecular Weight: 342.4567
• Mol File: 475094-43-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 487.9°Cat760mmHg
• Flash Point: 248.9°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 3.4E-09mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 5-METHYLTHIO-1,3,4-TRIPHENYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYLTHIO-1,3,4-TRIPHENYL-1H-PYRAZOLE(475094-43-0)
• EPA Substance Registry System: 5-METHYLTHIO-1,3,4-TRIPHENYL-1H-PYRAZOLE(475094-43-0)

Safety Data

• Hazardous Substances Data: 475094-43-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H18N2S/c1-25-22-20(17-11-5-2-6-12-17)21(18-13-7-3-8-14-18)23-24(22)19-15-9-4-10-16-19/h2-16H,1H3

Upstream product

• 32859-25-9 4-bromo-5-(methylthio)-1,3-diphenyl-1H-pyrazole 
• 98-80-6 phenylboronic acid 
• 66040-87-7 1,3-diphenyl-5-(methylthio)-1H-pyrazole 
• 1296269-70-9 4-iodo-5-(methylthio)-1,3-diphenyl-1H-pyrazole 
• 51507-11-0 3,3-bis(methylthio)-1,2-diphenylprop-2-en-1-one 
• 100-63-0 phenylhydrazine 

Relevant articles and documents

Mutant type IDH inhibitors, preparation method thereof, and pharmaceutical composition containg the same as an active ingredient

The present invention is a mutated IDH1 inhibitor. The present invention relates to a compound represented by chemical formula 1, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof according to the present invention, which has excellent inhibitory activity against mutated IDH1 and can reduce intracellular tumor-induced metabolite (2-HG), and a health functional food composition for preventing or IDH1 treating cancer, comprising the same as an active ingredient.

Regioselective synthesis of 1-aryl-3,4-substituted/annulated-5-(methylthio) pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/annulated pyrazoles

Highly efficient and regioselective synthesis of 1-aryl-3,4-substituted/ annulated-5-(methylthio)-pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/ annulated pyrazoles has been reported via cyclocondensation of arylhydrazines with either α-oxoketene dithioacetals or β-oxodithioesters.