475100-38-0Relevant academic research and scientific papers
Pd/Cu-Catalyzed Defluorinative Carbonylative Coupling of Aryl Iodides and gem-Difluoroalkenes: Efficient Synthesis of α-Fluorochalcones
Wu, Fu-Peng,Yuan, Yang,Liu, Jiawang,Wu, Xiao-Feng
, p. 8818 - 8822 (2021)
An unprecedented and challenging defluorinative carbonylation was achieved. Enabled by a Pd/Cu cooperative catalyst system, the first example of defluorinative carbonylative coupling has been established. With gem-difluoroalkenes and aryl iodides as the substrates, this methodology offers flexible and facile access to privileged α-fluorochalcones under mild reaction conditions in moderate-to-excellent yields. Mechanistic studies indicated transmetalation between palladium and copper intermediates as a crucial step of the catalytic cycle.
Synthesis and Reactivity of Fluorinated Triaryl Aluminum Complexes
Ould, Darren M. C.,Carden, Jamie L.,Page, Rowan,Melen, Rebecca L.
supporting information, p. 14891 - 14898 (2020/10/02)
The addition of the Grignard 3,4,5-ArFMgBr to aluminum(III) chloride in ether generates the novel triarylalane Al(3,4,5-ArF)3·OEt2. Attempts to synthesize this alane via transmetalation from the parent borane with trimethylaluminum gave a dimeric structure with bridging methyl groups, a product of partial transmetalation. On the other hand, the novel alane Al(2,3,4-ArF)3 was synthesized from the parent borane and trimethylaluminum. Interestingly, the solid-state structure of Al(2,3,4-ArF)3 shows an extended chain structure resulting from neighboring Al···F contacts. Al(3,4,5-ArF)3·OEt2 was then found to be an effective catalyst for the hydroboration of carbonyls, imines, and alkynes with pinacolborane.
Preparation method of polysubstituted aryl pinacol vinylboronate derivative
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Paragraph 0039; 0062-0064, (2019/02/10)
The invention discloses a preparation method of a polysubstituted aryl pinacol vinylboronate derivative and belongs to the technical field of preparation of chemical drugs. The method comprises the following steps: under an inert atmosphere, firstly, addi
Selective Dehydrogenative Mono- or Diborylation of Styrenes by Supported Copper Catalysts
Yoshii, Daichi,Jin, Xiongjie,Mizuno, Noritaka,Yamaguchi, Kazuya
, p. 3011 - 3016 (2019/04/13)
The selective dehydrogenative borylation of alkenes is an attractive method for synthesizing useful borylalkenes. However, very few catalytic systems have been reported that fulfill this objective. All the reported examples are homogeneous catalysts with
Synthetic method of alkenyl borate compound
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Paragraph 0041, (2019/12/02)
The invention relates to a synthesis method of an alkenyl borate compound, which comprises the following steps: dissolving an olefin compound and a borane compound in a solvent, adding a zirconium catalyst, reacting at 0-150 DEG C for 5 minutes to 8 hours
Superparamagnetic copper ferrite nanoparticles catalyzed aerobic, ligand-Free, regioselective hydroboration of alkynes: Influence of synergistic effect
Mohan, Balaji,Park, Kang Hyun
, p. 78 - 84 (2016/04/05)
We discovered a general and comprehensive approach for the regioselective hydroboration of terminal and internal alkynes to synthesize vinylboronates using inexpensive and magnetically separable copper ferrite nanoparticles at low catalyst loading using Bis(pinacolato)diboron in the absence of ligand and additives, under mild and greener conditions. A diverse range of functional groups was tolerated in the reaction, including allene and enones, and the corresponding boronates were obtained in high yields under air. Moreover, the assynthesized alkenylboronates were used as precursors to prepare wide variety of vinylorgano chalcogenides regioselectively, in high yields. The present protocol enable the conversion of Csp-H bonds to make Csp2-B bonds via activation of B-B bond, followed by formation of Csp2-Se (Te or S) bonds via activation of Se (Te or S)- Se (Te or S) bonds in a regioselective manner. Deuterium isotope labeling studies showed that the proton source of vinyl boronate stem from the solvent employed.
Synthesis of 1,1-organodiboronates via Rh(I)CI-catalyzed sequential regioselective hydroboration of 1-alkynes
Endo, Kohei,Hirokami, Munenao,Shibata, Takanori
experimental part, p. 1331 - 1335 (2009/10/23)
A Rh(I)Cl-DPPB-complex-catalyzed sequential hydroboration of aryl alkynes and aliphatic alkynes was achieved. The reaction proceeded with almost perfect regioselectivity to afford 1,1-organodiboronate compounds in moderate to good yield. Georg Thieme Verl
