475147-00-3Relevant articles and documents
Preparation of 2-arylated-1,4-phenylenediamines by palladium-catalyzed cross-coupling reactions
Jensen, Anne Eeg,Knochel, Paul
, p. 122 - 128 (2007/10/03)
Protected 2-iodol-1,4-phenylenediamines were converted to the corresponding magnesium derivative by performing an iodine-magnesium exchange. After transmetalation with zinc bromide, a palladium(0)-catalyzed cross-coupling with various aryl iodides and 5-bromo-2-carbethoxyfuran furnished the expected cross-coupling products in 52-79% yield.