475148-07-3Relevant academic research and scientific papers
Synthesis of a tetrabenzyl-substituted 10-membered cyclic diamide
Doi, Takayuki,Nagamiya, Hiroyuki,Kokubo, Masaya,Hirabayashi, Kazunori,Takahashi, Takashi
, p. 2957 - 2963 (2007/10/03)
A conformationally constrained 10-membered cyclic diamide was designed and synthesized. Conformational analysis suggested that the 9-membered ring formation was preferred to the direct formation of 10-membered ring. On the basis of the prediction, lactonization of 9-membered lactone, followed by intramolecular ester-amide transformation afforded the desired 10-membered cyclic diamide.
