475149-33-8

Upstream product

• 421592-49-6 3-t-butyldimethylsilyloxy-4-((4-ethylphenyl)methyl)-5-(trifluoromethyl)-1H-pyrazole 
• 2919-23-5 cyclobutanol 

Downstream Products

• 776317-25-0 1-cyclobutyl-4-[(4-ethylphenyl)methyl]-3-hydroxy-5-trifluoromethyl-1H-pyrazole 

Relevant academic research and scientific papers

PREVENTIVE/REMEDY FOR DIABETES

The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with the invention, hyperglycemia after meals, between meals and during fasting can be ameliorated. More specifically, in accordance with the invention, a therapeutic effect of diabetes mellitus as never been obtained by the hypoglycemic agents of the related art can be achieved.

N-SUBSTITUTED PYRAZOLYL-O-GLYCOSIDE DERIVATIVES AND REMEDIAL AGENT FOR DIABETES CONTAINING THE SAME

The present invention relates to pyrazole derivatives represented by the following formulas and analogues thereof, which can be used for a therapeutic agent for diabetes.