475150-37-9Relevant academic research and scientific papers
Synthesis of neoglycopeptides by chemoselective reaction of carbohydrates with peptides containing a novel N′-methyl-aminooxy amino acid
Carrasco, Michael R,Nguyen, Michael J,Burnell, Dawn R,MacLaren, Michael D,Hengel, Shawna M
, p. 5727 - 5729 (2002)
A novel N′-methyl-aminooxy amino acid has been designed, synthesized, and successfully incorporated into peptides using standard solid-phase peptide synthesis procedures. Reaction of these peptides with native reducing sugars yields neoglycopeptides via a
A Versatile Set of Aminooxy Amino Acids for the Synthesis of Neoglycopeptides
Carrasco, Michael R.,Brown, Ryan T.
, p. 8853 - 8858 (2007/10/03)
Four N-alkylaminooxy amino acids have been synthesized in 22-56% overall yield from readily available amino acid precursors. Each amino acid can be efficiently incorporated into peptides using Boc-chemistry-based solid-phase peptide synthesis, and in thre
