475272-55-0 Usage
General Description
(S)-1-Boc-3-benzylpiperazine is a chemical compound with the molecular formula C18H27N3O2. It is a piperazine derivative that is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. The compound is a white to off-white crystalline powder with a molecular weight of 317.42 g/mol. It is classified as a controlled substance in some countries due to its potential for abuse as a psychoactive drug. The compound is also known for its role as a precursor in the synthesis of various biologically active compounds, including antiviral and anticancer agents. Additionally, (S)-1-Boc-3-benzylpiperazine has been studied for its potential as a central nervous system stimulant and has shown promise in neuroprotective and cognitive enhancement applications.
Check Digit Verification of cas no
The CAS Registry Mumber 475272-55-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,2,7 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 475272-55:
(8*4)+(7*7)+(6*5)+(5*2)+(4*7)+(3*2)+(2*5)+(1*5)=170
170 % 10 = 0
So 475272-55-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H24N2O2/c1-16(2,3)20-15(19)18-10-9-17-14(12-18)11-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3/t14-/m0/s1
475272-55-0Relevant articles and documents
Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks
Crestey, Francois,Witt, Matthias,Jaroszewski, Jerzy W.,Franzyk, Henrik
supporting information; experimental part, p. 5652 - 5655 (2009/12/08)
(Chemical Equation Presented) This paper describes the first study of solution-phase synthesis of chiral monosubstituted piperazine building blocks from nosylamide-activated aziridines. The protocol, involving aminolysis of the starting aziridines with ω-amino alcohols and subsequent Fukuyama-Mitsunobu cyclization, offers the advantage of mild conditions as well as short reaction times, and it leads to optically pure N-Boc- or N-Ns-protected piperazines. This four-step sequence, requiring only a single final chromatographic purification, was extended to include novel diazepane and diazocane derivatives.
