475495-72-8Relevant academic research and scientific papers
Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines
Zeng, Chaoyuan,Yang, Fan,Chen, Jingchao,Wang, Jun,Fan, Baomin
, p. 8425 - 8428 (2015)
A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80-97% yields with 93-95% enantioselecti
Enantioselective synthesis of chiral 1,2-diamines by the catalytic ring opening of azabenzonorbornadienes: Application in the preparation of new chiral ligands
Cho, Yong-Hwan,Fayol, Aude,Lautens, Mark
, p. 416 - 427 (2007/10/03)
In the presence of a rhodium catalyst (5 mol %) generated in situ from [Rh(cod)Cl]2 and (S,S′)-(R,R′)-C2-ferriphos- tolyl, the asymmetric ring-opening reaction of N-Boc-azabenzonorbornadienes with dibenzylamine proceeded with excelle
Rhodium-catalyzed ring-opening reactions of N-boc-azabenzonorbornadienes with amine nucleophiles
Cho, Yong-Hwan,Zunic, Valentin,Senboku, Hisanori,Olsen, Madeline,Lautens, Mark
, p. 6837 - 6846 (2007/10/03)
In the presence of a rhodium catalyst (5 mol %) generated in situ from [Rh(cod)Cl]2 and (S, S′)-(R, R′)-C2-ferriphos (4a), the asymmetric ring-opening reaction of azabenzonorbornadienes (1a-m) with various aliphatic and aromatic amin
An expedient enantioselective route to diaminotetralins: application in the preparation of analgesic compounds.
Lautens, Mark,Fagnou, Keith,Zunic, Valentin
, p. 3465 - 3468 (2007/10/03)
Advances to the rhodium-catalyzed asymmetric ring-opening protocol have allowed this methodology to be extended to azabicyclic alkenes, the first time that rhodium has been used in allylic functionalizations with nitrogen leaving groups. The product diami
