475557-16-5Relevant academic research and scientific papers
Au(I)- and Pt(II)-catalyzed cycloetherification of ω-hydroxy propargylic esters
De Brabander, Jef K.,Liu, Bo,Qian, Mingxing
supporting information; experimental part, p. 2533 - 2536 (2009/05/26)
(Chemical Equation Presented) Depending on the nature of the metal catalyst, ω-hydroxy propargylic acetates choose between alternative cycloetherification manifolds to produce functionalized heterocycles in high yields. AuCl catalyzes the formation of oxacyclic enol acetates, whereas [Cl2Pt(CH2CH2)]2 (Zeise's dimer) will induce a propargylic substitution via an unprecedented S N2′-type allenic substitution from within a chelated square planar cationic Pt(II) complex.
Studies on Pd(II)-catalyzed synthesis of (Z)-α-haloalkylidene-β- lactones from cyclocarbonylation of 2-alkynols and the subsequent coupling reactions
Ma, Shengming,Wu, Bin,Jiang, Xuefeng,Zhao, Shimin
, p. 2568 - 2575 (2007/10/03)
(Chemical Equation Presented) A good regio- and stereoselectivity was observed for the PdCl2-catalyzed cyclocarbonylation of 2-alkynols with CuCl2 affording (Z)-α-chloroalkylidene-β-lactones. The highly optically active (Z)-α-chloroa
PdCl2-catalyzed efficient transformation of propargylic amines to (E)-α-chloroalkylidene-β-lactams
Ma, Shengming,Wu, Bin,Jiang, Xuefeng
, p. 2588 - 2593 (2007/10/03)
(Chemical Equation Presented) The PdCl2-catalyzed cyclocarbonylation reaction of propargylic amines with CuCl2 and benzoquinone afforded (E)-α-chloroalkylidene-β-lactams in moderate to good yields. The formation of the corresponding
Zn(ODf)2: Preparation and application in asymmetric alkynylation of aldehydes
Chen, Zili,Xiong, Wennan,Jiang, Biao
, p. 2098 - 2099 (2007/10/03)
A new Lewis acid, Zn(ODf)2, was first prepared from commercially available 3,3,4,4-tetrafluoro[1,2]oxathietane 2,2-dioxide in four steps with 56% yields and also was applied to catalyze highly enantioselective alkynylation of aldehydes in the presence of ligand (1S,2S)-3-(tert-butyldimethylsilyloxyl)-2-N,N-dimethylamino-1-(p- nitrophenyl)-propane-1-ol or ligand (-)-N-methylephedrine to afford the corresponding propargylic alcohols in high yields with up to 99% ee.
