475570-49-1Relevant articles and documents
Novel compounds for hypoxic cell therapy and imaging
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Page/Page column 17, (2010/11/24)
The present invention provides for compounds suitable for therapeutic treatment of hypoxic tissues, particularly for application in radiotherapy, chemosensitization, radiosensitization. The present invention further provides for compounds suitable for rad
Synthesis of 1-beta-D-(5-deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (beta-IAZA): a novel marker of tissue hypoxia.
Kumar, Piyush,Ohkura, Kazue,Beiki, Davood,Wiebe, Leonard Irving,Seki, Koh-ichi
, p. 399 - 403 (2007/10/03)
The present work describes the synthesis of the beta-isomer of 1-alpha-D-(5-deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (IAZA). Radioiodinated IAZA ((123)I-IAZA) has been extensively studied as a radiopharmaceutical for the diagnosis of regional and/or