475571-76-7

Upstream product

• 475571-79-0 5'-O-(tert-butyldimethylsilyl)-2'-deoxy-3'-O-methanesulfonyl-2'-phenylthiouridine 
• 475571-78-9 5'-O-(tert-butyldimethylsilyl)-2'-deoxy-2'-phenylthiouridine 
• 83087-95-0 2'-deoxy-2'-phenylthiouridine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant academic research and scientific papers

Sulfoxide-metal exchange for the synthesis of the 2'-tributylstannyl derivative of 2',3'-didehydro-2',3'-dideoxyuridine (d4u): a general entry to 2'-carbon-substituted analogues of d4U.

Methods are described for the synthesis of the 2'-tributylstannyl derivative of 2',3'-didehydro-2',3'-dideoxyuridine (d4U). Two approaches were investigated: radical-mediated desulfonylative stannylation of the 2'-benzenesulfonyl derivative of d4U and sul