475577-02-7

Basic information

• Product Name: 7-Bromo-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene
• Synonyms: 7-Bromo-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene
• CAS NO: 475577-02-7
• Molecular Weight: 464.113
• Mol File: 475577-02-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7-Bromo-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene(475577-02-7)
• EPA Substance Registry System: 7-Bromo-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene(475577-02-7)

Safety Data

• Hazardous Substances Data: 475577-02-7(Hazardous Substances Data)

Upstream product

• 475577-01-6 7-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2-imino-2H-chromene 
• 540-80-7 tert.-butylnitrite 
• 591-27-5 m-Hydroxyaniline 
• 6948-30-7 5-bromoveratralaldehyde 
• 339062-34-9 4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-2,7-diamino-4H-chromene 

Relevant articles and documents

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions

As a continuation of our efforts to discover and develop the apoptosis inducing 4-aryl-4H-chromenes as novel anticancer agents, we explored the SAR of 4-aryl-4H-chromenes with modifications at the 7- and 5-, 6-, 8-positions. It was found that a small hydr

Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted coumarins and quinolines and analogs thereof, represented by the general Formula I: wherein A, B, X, Y, and Z are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.