475596-16-8Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D2, serotonin, and GABAA receptors
Asproni, Battistina,Pau, Amedeo,Bitti, Mauro,Melosu, Marilena,Cerri, Riccardo,Dazzi, Laura,Seu, Emanuele,Maciocco, Elisabetta,Sanna, Enrico,Busonero, Fabiol,Talani, Giuseppe,Pusceddu, Luca,Altomare, Cosimo,Trapani, Giuseppe,Biggio, Giovanni
, p. 4655 - 4668 (2007/10/03)
A series of 18 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-piperazines (1a-r) were designed and synthesized as possible ligands with mixed dopamine (DA) D2/serotonin 5-HT1A affinity, with the aim of identifying novel compounds with ne
