475641-72-6

Upstream product

• 83938-00-5 ((2R,3S,6S)-3-acetoxy-6-cyano-3,6-dihydro-2H-pyran-2-yl)methyl acetate 
• 88180-36-3 2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl cyanide 
• 475641-63-5 (2R,4aR,6R,7R,8S,8aR)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-6-carbonitrile 
• 475641-64-6 (2R,4aR,6S,7R,8S,8aR)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-6-carbaldehyde 
• 475641-68-0 (2R,4aR,6R,7S,8R,8aS)-6-((R)-1-Hydroxy-but-3-enyl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 475641-62-4 (2R,4aR,6R,7S,8R,8aS)-7,8-Dihydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-6-carbonitrile 
• 2873-29-2 D-glucal triacetate 
• 88180-37-4 4,6-O-Benzylidene-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl cyanide 
• 475641-70-4 (2S,3R)-2-((2R,4S,5R)-4-Hydroxymethyl-2-phenyl-[1,3]dioxan-5-yloxy)-hex-5-ene-1,3-diol 
• 98-80-6 phenylboronic acid 

Downstream Products

• 475641-82-8 Chloro-methanesulfonic acid (2R,4S,5R)-5-((4R,5S)-4-allyl-2-phenyl-[1,3,2]dioxaborinan-5-yloxy)-2-phenyl-[1,3]dioxan-4-ylmethyl ester 
• 475641-84-0 Chloro-methanesulfonic acid (2R,4S,5R)-5-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-[1,3]dioxan-4-ylmethyl ester 
• 475641-89-5 (2R,4S,5R)-4-Allyl-5-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-[1,3]dioxane 
• 475641-86-2 {(2R,4S,5R)-5-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-[1,3]dioxan-4-yl}-acetonitrile 
• 475641-88-4 {(2R,4S,5R)-5-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-[1,3]dioxan-4-yl}-acetaldehyde 
• 475641-59-9 (Z)-(2R,4aR,6S,7R,11aS)-7-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-phenyl-4a,6,7,8,11,11a-hexahydro-4H-1,3,5-trioxa-benzocyclononene 
• 784157-75-1 Acetic acid (2R,4S,5R)-5-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-[1,3]dioxan-4-ylmethyl ester 
• 784157-60-4 (2R,4S,5R)-5-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-pent-4-enyloxy]-2-phenyl-4-vinyl-[1,3]dioxane 

Relevant academic research and scientific papers

Convergent synthesis of the ABCDE-ring part of ciguatoxin CTX3C

The ABCDE-ring part (2) of ciguatoxin CTX3C was concisely synthesized from the AB-ring and the E-ring parts (4 and 5).

Syntheses of the D-, E-, F-, and I-ring parts of ciguatoxin by a common strategy starting from tri-O-acetyl-D-glucal

Chiral medium-sized monocyclic ethers corresponding to the D-, E-, F-, and I-ring parts of ciguatoxin have been synthesized from tri-O-acetyl-D-glucal through a common synthetic route involving ring-closing olefin metathesis.