475644-95-2Relevant academic research and scientific papers
Synthesis of both enantiomers of flavanone and 2-methylchromanone
Noda, Yoshihiro,Watanabe, Morio
, p. 3473 - 3477 (2007/10/03)
An efficient enantiospecific synthesis of the (R)- and (S)-enantiomers of flavanone and 2-methylchromanone is described. The key steps are a C,C-bond formation by ring opening of a chiral epoxide with a dithiane anion, followed by a Mitsunobu cyclization. The products obtained have high enantiomeric purity.
