475984-83-9Relevant academic research and scientific papers
Synthesis of 9-methoxy and 9-acetoxy-3-amino-1-(4-methoxyphenyl)-1H-benzo[f]chromene-2-carbonitriles via 2-(imino-piperidin-1-yl-methyl)-3-(4-methoxyphenyl)acrylonitrile as intermediate
El-Agrody, Ahmed M.,Eid, Fathy A.,Emam, Hussein A.,Mohamed, Hany M.,Bedair, Ahmed H.
, p. 579 - 585 (2007/10/03)
Several new 1H-benzo[f]chromene derivatives (3a-d) were prepared by the reaction of 7-substituted-2-naphthols (1a,b) with substituted α-cyano-4-methoxycinnamonitriles (2a,b) together with 2-(imino-piperidin-1-yl-methyl)-3-(4-methoxyphenyl)acrylonitrile (4) as intermediate. Also, the reaction of 1a,b with 4 without catalyst afforded 9-methoxy and 9-acetoxy-3-amino-1-(p-methoxyphenyl)-1H-benzo[f]chromene-2-carbonitrile (3b,e). The reaction of 3a,b with different electrophilic and nucleophilic reagents afforded the 12H-7-oxa-8,10-diazabenzo[a]anthracene derivatives 5, 9, 10 and 1H-benzo[f]chromene derivatives 6-8, 11.
