476153-90-9

Upstream product

• 4105-60-6 2,3-O-isopropylidene-D-threo-4-pentenose 
• 139326-94-6 1,2:3,4-di-O-isopropylidene-5,6-di-O-mesyl-D-mannitol 
• 3969-59-3 mannitol triacetonide 
• 69-65-8 mannitol 
• 168109-89-5 (1R)-1-((4R,5R)-2,2-dimethyl-5-vinyl[1,3]dioxolan-4-yl)ethane-1,2-diol 
• 4239-90-1 (4S,4'R,5R)-2,2,2',2'-tetramethyl-5-vinyl-4,4'-bi(1,3-dioxolane) 
• 108-86-1 bromobenzene 

Downstream Products

• 1005208-26-3 3,4-O-isopropylidene-5-C-phenyl-5-O-(p-methoxybenzyl)-L-xylo-pent-1-en-3,4,5-triol 
• 476153-94-3 (1S,5S,7S,8R)-8-hydroxy-7-phenyl-2,6-dioxabicyclo[3.3.0]octan-3-one 
• 476153-92-1 (1S,2S,3R)-1-phenyl-pent-4-ene-1,2,3-triol 

Relevant academic research and scientific papers

The first total synthesis of goniothalesdiol

The first total synthesis of goniothalesdiol, a dihydroxylated tetrahydrofuran isolated from Goniothalamus borneensis (Annonaceae), and its 7-epimer is described starting with D-mannitol. The key step of these syntheses is palladium(II)-catalyzed oxycarbo

Stereoselective and facile total synthesis of (+)-goniodiol, a styryllactone from carbohydrates

The stereoselective synthesis of (+)-goniodiol, a cytotoxic styryllactone, has been accomplished in 10 steps starting from inexpensive and readily available d-manitol and δ-gluconolactone involving the direct and straightforward reaction conditions of Gri

Total syntheses of (+)-7-epi-goniofufurone, (+)-goniopypyrone and (+)-goniofufurone from a common precursor

Total syntheses of (+)-7-epi-goniofufurone, (+)-goniopypyrone and (+)-goniofufurone have been achieved from an advanced common precursor formed from d-(+)-mannitol by changing the carbinol protection profile. The Royal Society of Chemistry.

Synthesis of (+)-goniothalesdiol and (+)-7-epi-goniothalesdiol

A total synthesis of (+)-goniothalesdiol, a 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran isolated from Goniothalamus borneensis (Annonaceae), and its 7-epimer is reported using oxycarbonylation methodology for construction of polyhydroxylated substitut