476156-44-2

Upstream product

• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 476156-43-1 [(2'S,3'R,4'R,5'R)-3',4'-dibenzyloxy-N-tert-butyloxycarbonyl-5'-tert-butyldiphenylsilyloxymethylpyrrolidin-2'-yl]carbaldehyde 
• 476156-42-0 (2R,3R,4R,5R)-3,4-dibenzyloxy-N-tert-butyloxycarbonyl-2'-O-tert-butyldiphenylsilyl-2,5-bis(hydroxymethyl)pyrrolidine 

Downstream Products

• 476156-45-3 tert-butyl [(2R,3R,4R,5R)-3,4-bis(benzyloxy)-2-(tert-butyldiphenylsilyloxymethyl)-5-(3-oxobutyl)]pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

Polyhydroxylated pyrrolizidines. Part 2: The first total synthesis of (+)-hyacinthacine A3

The first total synthesis for the (+)-hyacinthacine A3 1 in a highly stereocontrolled manner, is reported herein. An appropriately protected polyhydroxylated pyrrolidine, such as (2R,3R,4R,5R)-3,4-dibenzyloxy-N-tert-butyloxycarbonyl-2′-O-tert-