476193-01-8Relevant academic research and scientific papers
MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres
Barta, Thomas E.,Becker, Daniel P.,Bedell, Louis J.,Easton, Alan M.,Hockerman, Susan L.,Kiefer, James,Munie, Grace E.,Mathis, Karl J.,Li, Madeleine H.,Rico, Joseph G.,Villamil, Clara I.,Williams, Jennifer M.
, p. 2820 - 2822 (2011/06/26)
Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.1a Here, we replace the amide moiety with non-hydrolyzable heterocycles
