476333-87-6Relevant academic research and scientific papers
Development of an Efficient Scale-Up Synthesis Method for a 3-Adrenergic Receptor Agonist, Ritobegron Ethyl Hydrochloride
Ainai, Takayuki,Isawa, Hidetoshi,Ishikawa, Takehiro,Kasai, Kiyoshi,Kikuchi, Norihiko,Kobayashi, Makoto,Kobayashi, Masahiro,Nakagawa-Goto, Kyoko,Nishimura, Masayuki,Ozawa, Tetsuji,Saito, Yohei,Sonehara, Junichi,Suzuki, Ritsu
, p. 1675 - 1682 (2020)
An efficient route for the multikilogram synthesis of a selective 3-adrenergic receptor agonist, ritobegron ethyl hydrochloride (1), was developed by changing the coupling method of 4-hydroxynorephedrine (2) with phenoxyacetate 3. This new method successf
INTERMEDIATES IN PRODUCING PHENOXYACETIC ACID DERIVATIVES AND METHOD OF USING THE SAME
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Page/Page column 8, (2010/02/11)
The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has β3-adrenoceptor stimulatin
