476335-09-8 Usage
Uses
(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-2-pentyl-4,6-methano-1,3,2-benzodioxaborole is an intermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate proteasome inhibitor.
Check Digit Verification of cas no
The CAS Registry Mumber 476335-09-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,3,3 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 476335-09:
(8*4)+(7*7)+(6*6)+(5*3)+(4*3)+(3*5)+(2*0)+(1*9)=168
168 % 10 = 8
So 476335-09-8 is a valid CAS Registry Number.
476335-09-8Relevant articles and documents
P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease
Priestley,De Lucca, Indawati,Ghavimi, Bahman,Erickson-Viitanen, Susan,Decicco, Carl P.
, p. 3199 - 3202 (2007/10/03)
A series of peptide boronic acids containing extended, hydrophobic P1 residues was prepared to probe the shallow, hydrophobic S1 region of HCV NS3 protease. The p-trifluoromethylphenethyl P1 substituent was identified as optimal with respect to inhibitor potency for NS3 and selectivity against elastase and chymotrypsin.
