476437-57-7Relevant academic research and scientific papers
Enantioselective Total Synthesis of (+)-Plumisclerin A
Gao, Ming,Wang, Ye-Cheng,Yang, Kai-Rui,He, Wei,Yang, Xiao-Liang,Yao, Zhu-Jun
, p. 13313 - 13318 (2018)
The first and enantioselective total synthesis of (+)-plumisclerin A, a novel unique complex cytotoxic marine diterpenoid, has been accomplished. Around the central cyclopentane anchorage, a sequential ring-formation protocol was adopted to generate the c
Highly enantioselective catalytic Michael reaction of α-substituted malonates using La-linked-BINOL complex in the presence of HFIP (1,1,1,3,3,3-hexafluoroisopropanol)
Takita, Ryo,Ohshima, Takashi,Shibasaki, Masakatsu
, p. 4661 - 4665 (2007/10/03)
A catalytic asymmetric Michael reaction of α-substituted malonates with broad generality was developed using the La-linked-BINOL complex. To enhance the reactivity of unreactive α-substituted malonates, we examined the effects of concentration and additiv
