476443-52-4

Upstream product

• 116836-27-2 2-amino-8-methylquinazolin-4(3H)-one 
• 22223-49-0 methyl 2-amino-3-methylbenzoate 

Downstream Products

• 476444-58-3 N-[6-amino-3,4-dihydro-4-oxo-8-(phenoxymethyl)quinazolin-2-yl]-2,2-dimethylpropanamide 
• 476444-50-5 N-{6-amino-3,4-dihydro-4-oxo-8-[(phenylsulfanyl)methyl]quinazolin-2-yl}-2,2-dimethylpropanamide 
• 447415-51-2 N-[3,4-dihydro-6-nitro-4-oxo-8-(phenoxymethyl)quinazolin-2-yl]-2,2-dimethylpropanamide 
• 447415-47-6 N-{3,4-dihydro-6-nitro-4-oxo-8-[(phenylsulfanyl)methyl]quinazolin-2-yl}-2,2-dimethylpropanamide 
• 785817-54-1 N-(6-amino-8-{[(3-bromophenyl)sulfanyl]methyl}-3,4-dihydro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 
• 476443-77-3 N-{6-amino-8-[(cyclohexylsulfanyl)methyl]-3,4-dihydro-4-oxoquinazolin-2-yl}-2,2-dimethylpropanamide 
• 785817-35-8 N-(8-{[(3-bromophenyl)sulfanyl]methyl}-3,4-dihydro-6-nitro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 
• 447415-35-2 N-{8-[(cyclohexylsulfanyl)methyl]-3,4-dihydro-6-nitro-4-oxoquinazolin-2-yl}-2,2-dimethylpropanamide 
• 785817-56-3 N-(6-amino-8-{[([1,1'-biphenyl]-3-yl)sulfanyl]methyl}-3,4-dihydro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 
• 785817-37-0 N-(8-{[([1,1'-biphenyl]-3-yl)sulfanyl]methyl}-3,4-dihydro-6-nitro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 

Relevant academic research and scientific papers

Synthesis and in vitro evaluation of 2-aminoquinazolin-4(3H)-one-based inhibitors for tRNA-guanine transglycosylase (TGT)

tRNA-Guanine transglycosylase (TGT) plays a key role in the post-transcriptional modification of tRNA. It has been linked with the pathogenicity of shigellae, the causative agents of bacillary dysentery (shigellosis). Here, we report structure-activity re