785817-56-3

Upstream product

• 447415-30-7 N-[8-(bromomethyl)-3,4-dihydro-6-nitro-4-oxoquinazolin-2-yl]-2,2-dimethylpropanamide 
• 476443-53-5 N-(3,4-dihydro-8-methyl-6-nitro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 
• 476443-52-4 2-amino-8-methyl-6-nitroquinazolin-4(3H)-one 
• 116836-27-2 2-amino-8-methylquinazolin-4(3H)-one 
• 22223-49-0 methyl 2-amino-3-methylbenzoate 
• 51193-27-2 [1,1′-biphenyl]-3-thiol 
• 785817-37-0 N-(8-{[([1,1'-biphenyl]-3-yl)sulfanyl]methyl}-3,4-dihydro-6-nitro-4-oxoquinazolin-2-yl)-2,2-dimethylpropanamide 

Relevant academic research and scientific papers

Synthesis and in vitro evaluation of 2-aminoquinazolin-4(3H)-one-based inhibitors for tRNA-guanine transglycosylase (TGT)

tRNA-Guanine transglycosylase (TGT) plays a key role in the post-transcriptional modification of tRNA. It has been linked with the pathogenicity of shigellae, the causative agents of bacillary dysentery (shigellosis). Here, we report structure-activity re