476470-99-2Relevant academic research and scientific papers
Visible Light Photoredox Cross-Coupling of Acyl Chlorides with Potassium Alkoxymethyltrifluoroborates: Synthesis of α-Alkoxyketones
Amani, Javad,Sodagar, Esmat,Molander, Gary A.
supporting information, p. 732 - 735 (2016/03/01)
A visible-light, single-electron-transfer (SET), photoredox cross-coupling for the synthesis of α-alkoxyketones has been developed. In this method, various aliphatic and aromatic acyl chlorides were successfully coupled with structurally diverse potassium
Non-peptidic small molecule inhibitors of XIAP
Park, Cheol-Min,Sun, Chaohong,Olejniczak, Edward T.,Wilson, Alan E.,Meadows, Robert P.,Betz, Stephen F.,Elmore, Steven W.,Fesik, Stephen W.
, p. 771 - 775 (2007/10/03)
Non-peptidic small molecule SMAC mimetics were designed and synthesized that bind to the BIR3 domain of XIAP using structure-based design. Substituted five-membered heterocycles such as thiazoles and imidazoles were identified that serve as replacements for peptide fragments of the lead.
