477203-69-3Relevant academic research and scientific papers
Concise Synthesis of Dictyoquinazol A via a Dimerisation-Cyclocondensation Sequence
Wangsahardja, Jonatan,Marcolin, Gabriella M.,Lizarme, Yuvixza,Morris, Jonathan C.,Hunter, Luke
, p. 1237 - 1240 (2016/05/10)
A two-step total synthesis of the neuroprotective alkaloid, dictyoquinazol A, has been achieved. The brevity of this synthesis was enabled by exploiting the hidden symmetry of the target molecule. Several structural analogues were also prepared using a similar strategy. These results provide a platform for future structure-activity relationship studies in the quest for a novel treatment for stroke.
Synthesis and neuroprotective activity of dictyoquinazol A and analogues
Lizarme, Yuvixza,Wangsahardja, Jonatan,Marcolin, Gabriella M.,Morris, Jonathan C.,Jones, Nicole M.,Hunter, Luke
, p. 1480 - 1487 (2016/03/16)
A flexible and efficient synthesis of the neuroprotective alkaloid, dictyoquinazol A, is reported. Several structural analogues of the target molecule were produced, and the neuroprotective activity of this series of compounds was investigated using three
Total synthesis of neuroprotective dictyoquinazol A, B, and C
Oh, Chang Ho,Song, Chung Hyun
, p. 3311 - 3317 (2008/02/13)
A new protective compound, dictyoquinazol A, was synthesized starting from 5-methoxy-2-nitrobenzoic acid in six-steps in 36% overall yield. Two derivatives B and C, isolated from the mushroom Dictyophora indusiata, were also synthesized from Dictyoquinazo
