477218-70-5Relevant articles and documents
2,5-Dimethylphenacyl as a New Photoreleasable Protecting Group for Carboxylic Acids
Klan, Petr,Zabadal, Miroslav,Heger, Dominik
, p. 1569 - 1571 (2000)
(Matrix Presented) The 2,5-dimethylphenacyl chromophore, a new photoremovable protecting group for carboxylic acids, is proposed. Direct photolysis of various 2,5-dimethylphenacyl esters in benzene or methanol at 254-366 nm leads to the formation of the corresponding carboxylic acids in almost quantitative isolated yields. The photodeprotection is based on efficient intramolecular hydrogen abstraction without the necessity of introducing a photosensitizer.