50690-11-4

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 2-chloro-1-(2,5-dimethylphenyl)(9CI) serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with improved therapeutic properties and targeted effects.
Used in Agrochemical Industry:
In the agrochemical sector, Ethanone, 2-chloro-1-(2,5-dimethylphenyl)- (9CI) is employed as a building block for the creation of novel agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their efficacy and selectivity, leading to more effective and environmentally friendly solutions for agricultural challenges.
Used in Materials Science:
Ethanone, 2-chloro-1-(2,5-dimethylphenyl)(9CI) also finds applications in the field of materials science, where it can be used to develop new materials with specific properties. Its unique structure and reactivity make it a promising candidate for the synthesis of advanced materials with applications in various industries.
Used in Research Laboratories:
Ethanone, 2-chloro-1-(2,5-dimethylphenyl)(9CI) is a valuable reagent in research laboratories, where it is used as a building block for the creation of new compounds. Its versatility and reactivity make it an essential tool for chemists working on the development of novel chemical entities and exploring new reaction pathways.

InChI:InChI=1/C10H11ClO/c1-7-3-4-8(2)9(5-7)10(12)6-11/h3-5H,6H2,1-2H3

Upstream product

• 106-42-3 para-xylene 
• 79-04-9 chloroacetyl chloride 
• 79-11-8 chloroacetic acid 

Downstream Products

• 24623-20-9 2,3-dihydro-6-methyl-1H-inden-1-one 
• 66521-22-0 2-(methoxymethyl)-5-methylacetophenone 
• 528-44-9 1,2,4-benzene tricarboxylic acid 
• 378215-21-5 2,5-dimethylphenacyl benzoate 
• 378215-25-9 2,5-dimethylphenacyl phenylacetate 
• 477218-70-5 2,5-dimethylphenacyl palmitate 
• 378215-29-3 2-(2,5-dimethylphenyl)-2-oxoethyl acetate 
• 13612-34-5 2-(2,5-dimethylphenyl)acetic acid 
• 103985-99-5 4-(2,5-dimethyl-phenyl)-3H-thiazol-2-one 
• 915085-47-1 2-(n-butoxymethyl)-5-methyl-α-chloroacetophenone 
• 915085-44-8 2-(ethoxymethyl)-5-methyl-α-chloroacetophenone 
• 134486-23-0 2-Chloro-1-[3-methyl-6-methylene-cyclohexa-2,4-dien-(Z)-ylidene]-ethanol 

Relevant academic research and scientific papers

Chloroacetylation of arenes using chloroacetyl chloride in the presence of FeCl3 modified montmorillonite K10

Chloroacetylation reaction of arenes using chloroacetyl chloride has been studied in the presence of Fe-modified montmorillonite K10 catalysts in a liquid phase. The catalysts have been prepared by treating montmorillonite K10 with aqueous solution of FeCl3. Good yields and selectivity are observed for the acylated product.

METHOD FOR PRODUCING 2,5-DIMETHYLPHENYL ACETIC ACID

The invention relates to a method for producing 2,5-dimethylphenyl acetic acid by reacting p-xylol with chloroacetyl chloride to form 2-chloro-1-(2,5-dimethylphenyl) ethanone, which reacts with the compound of formula (II) to form the compound of formula (III). The latter is then rearranged into a mixture of compounds (IV) and (V), which is then saponified to form 2,5-dimethylphenyl acetic acid. (II) (III) (IV) (V).

Antimony(V) chloride-benzyltriethylammonium chloride complex as an efficient catalyst for friedel-crafts acylation reactions

A novel catalytic system, the complex of antimony(V) chloride (SbCl 5) and benzyltriethylammonium chloride (TEBA), C6H 5CH2NEt3(SbCl5)2Cl complex, is described for Friedel-Crafts acylation reactions of aromatics with acyl and sulfonyl chlorides. The catalyst has a number of useful characteristics, such as ready access, minimal toxicity, reusability, insensitivity to atmosphere and moisture, rapid acylation with high yield, and ease of operation.

Photoenolization with α-Chloro Substituents

Irradiation of a methanol solution of 2,5-dimethyl-α-chloropropiophenone (1a) produces 2,6-dimethyl-1-indanone (2a), 2-(methoxymethyl)-5-methylpropiophenone (3a), 2,5-dimethylpropiophenone (4a), and methyl 2-(2,5-dimethylphenyl)propionate (5a).It is proposed that the first two products arise from hydrogen abstraction followed by chlorine loss, the latter two from initial loss of chlorine.Making the chlorine-bearing carbon primary suppresses the formation of the latter two products, while maintaining the carbonyl nearly planar with the ring suppresses all product formation.Other examples are presented.